Spinal Cord Stimulation Assisted by Motor Rehabilitation Training for Restoring Motor Function After Spinal Cord Injury

Technology
Standing/walking/mobility
Online since 7 December 2023, updated 221 days ago

About this trial

This trial is enrolling 10 individuals with chronic spinal cord injury to test the effect of spinal cord stimulation (SCS) followed by walking training on lower limb movement. SCS is a technique for stimulating the spinal cord with implanted electrodes placed next to the spinal cord to modify spinal cord function. If included, participants will undergo surgery to implant the stimulation device next to the spinal cord. After a recovery period, participants will receive at least 6 weeks of SCS combined with step/stand training. Final testing of lower limb movement will be performed 6 months after the surgery.

Included participants

Gender
All
Age
≥ 18 years
Injury level
C1 - S5
  • Severity (AIS)?
  • AIS-A
    AIS-B
    AIS-C
    Time since injury
    ≥ 1 year
    Healthy volunteers
    No
    C1-S5
    Additionally, participants must
    NOT have any significant psuchiatric disease

    What’s involved

    Type

    Technology

    Details

    - Participants will undergo spinal cord stimulation (SCS) surgery, which involves the implantation of a electrodes next to the spinal cord - Following a recovery period, participants will receive a combination of SCS with manual step/stand training for at least 6 weeks. - Final testing of lower limb movement will be performed 6 months after the surgery.

    Potential benefits

    Main benefits

    Standing/walking/mobility

    Additional benefits

    General health

    Pain

    Sensory function

    Spasticity

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 19 Apr 2023
    • Organisation
    • IRCCS San Raffaele
    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 19 Apr 2023
    • Organisation
    • IRCCS San Raffaele

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more