Epidural Stimulation in Chronic Spinal Cord Injury Patients

About this trial

This trial is enrolling 5 individuals with chronic spinal cord injuries between C7 and T10 to test the effect of epidural stimulation (ES) on autonomic and leg function. ES is a technique for stimulating the spinal cord with a surgically implanted electrode placed next to the spinal cord. If included, participants will receive 80 sessions of ES. Brain imaging will be performed with magnetic resonance imaging before and after the intervention. Investigators will measure leg function as well as changes in trunk stability, bowel and bladder function, spasticity, pain, blood pressure, sexual function, and quality of life. Final testing will be performed after 1 year.