Intervention on Bone Health in Wheelchair Users

Rehabilitation
Bone health
Online since 13 January 2023, updated 402 days ago

About this trial

The low mechanical loading of bones among wheelchair users leads to an increased risk of bone fractures and associated complications due to low bone mineral density (BMD). Adding mechanical loading th...

Included participants

Gender
All
Age
18 - 50 years
Injury level
T6 - S5
  • Severity (AIS)?
  • Time since injury
    ≥ 2 years
    Healthy volunteers
    Yes
    T6-S5

    What’s involved

    Type

    Rehabilitation

    Details

    The primary aim of this project is to investigate the effects of combined exercise training with high mechanical loading of bones and nutritional counselling for improving bone health in wheelchair users with an initially low-normal to low BMD (Z-score ≤ 0.0). Specifically, the following objectives are to determine the effects of the intervention on: Bone health, measured as changes in BMD and blood bone markers. Physical health, including body composition and muscular fitness. Mental health, with focus on well-being, QOL and user experience. Our secondary aim is to use this knowledge to develop recommendations and implementation plans for exercise and nutrition to promote bone health of wheelchair users. Using a randomized controlled design, participants will undergo an exercise intervention in which the participants also will receive nutritional optimization for bone remodelling. Main outcomes are change in BMD, blood bone markers, physical health and mental health parameters. Based on the outcomes of the RCT, we will develop evidence-based practical health promoting recommendations and an implementation plan for health practitioners working with wheelchair users in the municipalities.

    Potential benefits

    Main benefits

    Bone health

    Additional benefits

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

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    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 1 Dec 2022
    • Organisation
    • Norwegian School of Sport Sciences
    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 1 Dec 2022
    • Organisation
    • Norwegian School of Sport Sciences

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more