Transcranial Magnetic Stimulation for Chronic Neuropathic Pain

Technology

Mental health and psychosocial factors

Online since 12 March 2024, updated 283 days ago

About this trial

This trial is enrolling individuals with spinal cord injuries to test the effect of repetitive transcranial magnetic stimulation (rTMS) on neuropathic pain. rTMS is FDA approved to treat major depressive disorder, obsessive-compulsive disorder and migraine but its effect on neuropathic pain is variable so far. This trial of rTMS scalp surface stimulation targeting specific areas of the brain associated with pain processing is using different amounts of stimulation to understand the effect on neuropathic pain. If included, participants will undergo either: 10 sessions of high frequency rTMS (3000 pulses per session); or 10 sessions of low frequency rTMS (300 pulses per session). Final testing will be performed after 6 months.

Included participants

Gender

All

Age

18 - 80 years

Injury level

C1 - S5

Severity (AIS)?

Time since injury

All

Healthy volunteers

C1-S5

Additionally, participants must

meet criteria for chronic neuropathic pain

NOT have implanted device

What’s involved

Type

Technology

Details

If included, participants will undergo either 1) 10 sessions of high frequency rTMS (10 Hz, 3000 pulses per session) or 2) 10 sessions of low frequency rTMS (1 Hz, 300 pulses per session).

Potential benefits

Main benefits

Mental health and psychosocial factors

Additional benefits

Pain

Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

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Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

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