Effect of Hypercapnia Treatment on Respiratory Recovery After Spinal Cord Injury
About this trial
This trial is enrolling individuals with chronic spinal cord injuries to test the feasibility of daily acute intermittent hypercapnia (dAIHc) and its effect on respiratory function and sleep apnea. dAIHc is a technique to strengthen respiratory muscles. Sleep apnea (where your breathing stops and starts while breathing) can prevent your body from getting enough oxygen and may require an external device with pressurized air to keep your breathing steady. The investigators hypothesize that daily hypercapnia treatments (delivering higher than normal amounts of a gas called carbon dioxide) may improve respiratory function and sleep apnea. If included, participants will undergo either: 1) active dAIHc treatment; or 2) a sham intervention (pressurized air). Each arm includes 5 treatment days per week, for two weeks. Final testing will be performed at the end of the two week period.
Included participants
What’s involved
Type
Details
- Participants will undergo either 1) active dAIHc or 2) a sham intervention 5 days per week, for two weeks - Final testing will be performed after 2 weeks
Potential benefits
Main benefits
General health
Additional benefits
Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.
Wings for Life supports SCITrialsFinder
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more- Trial recruitment status
- Recruiting
- Trial start date
- 1 Mar 2023
- Organisation
- VA Office of Research and Development
- Trial recruitment status
- Recruiting
- Trial start date
- 1 Mar 2023
- Organisation
- VA Office of Research and Development
About this trial
Included participants
What’s involved
Potential benefits
Wings for Life supports SCITrialsFinder
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more