Neuropathic Pain and Operant Conditioning of Cutaneous Reflexes After SCI

Technology
Pain
Online since 7 October 2024, updated yesterday

About this trial

This trial is enrolling 15 individuals with chronic spinal cord injury to test the effect of reflex training in the leg on neuropathic pain. If included, participants will receive 6 baseline sessions and 30 sessions of reflex stimulation in the lower limb. While the participant is standing, nerves in the lower leg and ankle are stimulated to activate a spinal reflex. Participants use visual feedback to increase or decrease reflex activity. Final testing will be performed after about 6 months.

Included participants

Gender
All
Age
≥ 18 years
Injury level
C1 - S5
  • Severity (AIS)?
  • Time since injury
    ≥ 1 year
    Healthy volunteers
    No
    C1-S5
    Additionally, participants must
    have neuropathic pain in lower leg
    NOT have peripheral neuropathy
    NOT have motoneuron injury

    What’s involved

    Type

    Technology

    Details

    -participants will receive 6 baseline sessions and 30 sessions of reflex stimulation in the lower limb Final testing will be performed after 3 months

    Potential benefits

    Main benefits

    Pain

    Additional benefits

    Bladder health/function

    Bowel health

    Mental health and psychosocial factors

    Sensory function

    Standing/walking/mobility

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 27 Mar 2023
    • Organisation
    • Medical University of South Carolina
    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 27 Mar 2023
    • Organisation
    • Medical University of South Carolina

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more