Closed-loop Spinal Stimulation for Restoration of Upper Extremity Function After Spinal Cord Injury
About this trial
This is a trial enrolling individuals with chronic cervical spinal cord injuries to test the effect of transcutaneous electrical spinal cord stimulation (TSCS) on upper limb function. TSCS is a technique for stimulating the spinal cord via skin surface electrodes, in this case applied to the skin on the back of the neck. If included, participants will undergo repeated baseline measurements throughout four weeks, followed by intensive exercise therapy for six weeks. Then they will undergo either: 1) continuous TSCS(open-loop); or 2) activity-specific TSCS (closed-loop), followed by a 6-week waiting period without stimulation. Then they will receive the other intervention (closed or open-loop) for another 6 weeks. Each session will last 90 minutes, three sessions per week. Overall participation in the study will last ten months. The trial will include repeated measurements of arm and hand strength, sensation and function. Spasticity will also be assessed.
Included participants
Traumatic
What’s involved
Type
Details
1) Repeated baseline measurements throughout four weeks, 2) Intensive exercise therapy for six weeks 3) Either i. continuous TSCS(open-loop) or ii. activity-specific TSCS (closed-loop) for 6 weeks 4) 6-week waiting period without stimulation 5) The other intervention (closed or open-loop) for another 6 weeks - Each session will last 90 minutes, three sessions per week. - Final testing will be performed at a 12 week follow up, for a total participation of 10 months
Potential benefits
Main benefits
Arm/hand function
Additional benefits
Sensory function
Spasticity
Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.
Wings for Life supports SCITrialsFinder
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more- Trial recruitment status
- Recruiting
- Trial start date
- 12 Oct 2022
- Organisation
- University of Washington
- Trial recruitment status
- Recruiting
- Trial start date
- 12 Oct 2022
- Organisation
- University of Washington
About this trial
Included participants
What’s involved
Potential benefits
Wings for Life supports SCITrialsFinder
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more