Dosing of Overground Robotic Gait Training With Functional Outcomes and Neuroplasticity After Spinal Cord Injury

Rehabilitation
Standing/walking/mobility
Online since 12 March 2024, updated 100 days ago

About this trial

This trial is enrolling individuals with recent incomplete spinal cord injuries undergoing inpatient rehabilitation to test the effect of robotic gait training (RGT), using an externally worn powered robotic device (exoskeleton) to assist walking movement. If included, participants will undergo either: 1) one inpatient exoskeleton training session followed by two outpatient sessions of RGT per week for 12 weeks; 2) one inpatient exoskeleton training session followed by three outpatient sessions of RGT per week for 8 weeks, 3) one inpatient exoskeleton training session followed by four outpatient sessions of RGT per week for 6 weeks, or 4) standard inpatient gait training without RGT. Each session will last 45 minutes. Final testing will be performed 9 months after injury, including measures of walking function, Motor Evoked Potentials using non-invasive transcranial magnetic stimulation, pain, fatigue and life satisfaction .

Included participants

Gender
All
Age
16 - 85 years
Injury level
C1 - S5
  • Severity (AIS)?
  • AIS-C
    AIS-D
    Time since injury
    ≤ 6 months
  • Injury type
  • Traumatic

    Non-traumatic

    Healthy volunteers
    No
    C1-S5
    Additionally, participants must
    Be currently undergoing medical care and rehabilitation at Baylor Scott & White Institute for Rehabilitation
    Must meet the Ekso Robotic frame size specification (height 5' to 6'4", weight 220lbs or less)

    What’s involved

    Type

    Rehabilitation

    Details

    - Participants will undergo either 1) 2 sessions of RGT per week for 12 weeks, 2) 3 sessions of RGT per week for 8 weeks, 3) 4 sessions of RGT per week for 6 weeks, or 4) standard gate training without RGT. - Each session will last 45 minutes. - Final testing will be performed 9 months after injury.

    Potential benefits

    Main benefits

    Standing/walking/mobility

    Additional benefits

    General health

    Mental health and psychosocial factors

    Pain

    Spasticity

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 20 May 2022
    • Organisation
    • Baylor Research Institute
    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 20 May 2022
    • Organisation
    • Baylor Research Institute

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more