Detrusor Activity Recovery in Acute Traumatic Spinal Cord Injuries

Bladder health
Online since 13 March 2022, updated 564 days ago

About this trial

Determining the most appropriate time to evaluate detrusor activity in urodynamic studies for both traumatic and non-traumatic spinal cord injuries...

Included participants

Gender
All
Age
18 - 75 years
Injury level
Level not specified
  • Severity (AIS)?
  • Time since injury
    ≤ 15 days
  • Injury type
  • Traumatic

    Non-traumatic

    Healthy volunteers
    No
    Level not specified

    What’s involved

    Type

    Observational

    Details

    The detrusor activity in the acute phase of the spinal cord injury changes with the development of the spinal shock. Spinal shock is a phase of areflexic phase after the spinal cord injury that is primarily influenced by the severity of the injury and the neurological level of injury. Detrusor activity shows areflexic in the spinal shock phase, followed by a return of detrusor activity at the end of the spinal shock. There was no recent study to provide evidence of an appropriate time to assess detrusor muscle activity through urodynamic studies. There were only a few limited studies on detrusor activity following spinal cord injury from 1960 to 1970. However, when the urodynamic study should be performed is still controversial. Knowing the patterns of detrusor activity following spinal cord injuries is critical to determining the appropriate timing for intermittent catheterization, which is the standard emptying method of choice. If clinicians fail to understand true detrusor activity as early as possible, the patient will suffer from unnecessary indwelling catheter voiding, resulting in impaired quality of life in the acute phase.

    Potential benefits

    Main benefits

    Bladder health

    Additional benefits

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Recruiting soon
    • Trial start date
    • 1 Mar 2022
    • Organisation
    • Pusan National University Yangsan Hospital
    • Trial recruitment status
    • Recruiting soon
    • Trial start date
    • 1 Mar 2022
    • Organisation
    • Pusan National University Yangsan Hospital

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more