Treatment With Romosozumab to Improve Bone Mineral Density and Architecture in Chronic SCI

Drug
Bone health
Online since 13 March 2022, updated 997 days ago

About this trial

The objective of the proposed work is to determine whether administration for 12 months of romosozumab followed by 12 months of denosumab will maintain bone mass at the knee in subjects with chronic S...

Included participants

Gender
All
Age
18 - 50 years
Injury level
C4 - S5
  • Severity (AIS)?
  • AIS-A
    AIS-B
    AIS-C
    Time since injury
    3 years - 15 years
    Healthy volunteers
    No
    C4-S5
    Additionally, participants must
    be wheelchair dependent greater than 75% of the time

    What’s involved

    Type

    Drug

    Details

    There are no details yet

    Potential benefits

    Main benefits

    Bone health

    Additional benefits

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 1 Mar 2021
    • Organisation
    • James J. Peters Veterans Affairs Medical Center
    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 1 Mar 2021
    • Organisation
    • James J. Peters Veterans Affairs Medical Center

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more