Treatment With Romosozumab to Improve Bone Mineral Density and Architecture in Chronic SCI

Drug

Bone health

Online since 13 March 2022, updated 1013 days ago

About this trial

The objective of the proposed work is to determine whether administration for 12 months of romosozumab followed by 12 months of denosumab will maintain bone mass at the knee in subjects with chronic S...

Included participants

Gender

All

Age

18 - 50 years

Injury level

C4 - S5

Severity (AIS)?

AIS-A

AIS-B

AIS-C

Time since injury

3 years - 15 years

Healthy volunteers

C4-S5

Additionally, participants must

be wheelchair dependent greater than 75% of the time

What’s involved

Type

Drug

Details

There are no details yet

Potential benefits

Main benefits

Bone health

Additional benefits

Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

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