Spinal Cord Stimulation and Respiration After Injury

Alternative or complimentary methods
General health
Online since 9 September 2022, updated 529 days ago

About this trial

This trial is enrolling individuals with chronic spinal cord injuries to test the effect combining epidural spinal cord stimulation (scES) with respiratory training. scES is a technique for stimulating the spinal cord via implanted electrode placed next to the spinal cord to modify spinal cord function. If included, participants will perform either: 1) respiratory training during scES; 2) respiratory training alone; or 3) scES alone during 45-minute session for 16 weeks. Researchers want to see if the combination strategy of stimulation and training improves respiratory and/or motor function.

Included participants

Gender
All
Age
≥ 18 years
Injury level
C3 - T1
  • Severity (AIS)?
  • AIS-A
    AIS-B
    AIS-C
    Time since injury
    ≥ 24 months
    Healthy volunteers
    No
    C3-T1
    Additionally, participants must
    have at least a 15%-deficit in pulmonary function outcomes
    NOT be ventilator dependent

    What’s involved

    Type

    Alternative or complimentary methods

    Details

    - Participants will perform either 1) respiratory training during scES, 2) respiratory training alone, 3) scES alone during 45-minute session for 16 weeks. - Final testing will be performed after 1 year.

    Potential benefits

    Main benefits

    General health

    Additional benefits

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 31 Dec 2021
    • Organisation
    • University of Louisville
    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 31 Dec 2021
    • Organisation
    • University of Louisville

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more