A Clinical Trial of Cognitive Multisensory Rehabilitation for Sensory and Motor Recovery in Adults With Spinal Cord Injury

Rehabilitation
Arm/hand function
Online since 15 August 2023, updated 188 days ago

About this trial

This trial is enrolling individuals with spinal cord injuries for at least 3 months to test the effect of Cognitive Multisensory Rehabilitation (CMR) versus adaptive fitness on sensory and motor function. CMR includes body awareness exercises, proprioception training (the ability to sense movement, action, and location) and texture discrimination tasks. The investigators want to see if CMR restores brain connections related to sensory and motor function by strengthening certain brain networks. If included, participants will undergo: 1) CMR for 8 weeks, 3 times a week, for 45 minutes; or 2) adaptive fitness training for 8 weeks, 3 times a week, for 45 minutes. Changes in brain activation and connectivity will be measured using functional Magnetic Resonance Imaging (fMRI). Mood, life satisfaction, and community integration will also be assessed.

Included participants

Gender
All
Age
18 - 75 years
Injury level
C1 - S5
  • Severity (AIS)?
  • AIS-A
    AIS-B
    AIS-C
    AIS-D
    Time since injury
    ≥ 3 months
  • Injury type
  • Traumatic

    Non-traumatic

    Healthy volunteers
    No
    C1-S5
    Additionally, participants must
    NOT have cognitive impairments

    What’s involved

    Type

    Rehabilitation

    Details

    - the participant will undergo 1) CMR for 8 weeks, 3x/week, for 45 min or 2) adaptive fitness training for 8 weeks, 3x/week, for 45 min - clinical assessments will be performed at baseline, after the 8 week intervention, and 3 months after the trial. - MRI scans will be performed at baseline and after the 8 week intervention

    Potential benefits

    Main benefits

    Arm/hand function

    Additional benefits

    General health

    Mental health

    Pain

    Sensory function

    Standing/walking/mobility

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 1 Jun 2022
    • Organisation
    • University of Minnesota
    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 1 Jun 2022
    • Organisation
    • University of Minnesota

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more