Spinal Cord Associative Plasticity Study

Technology
Arm/hand function
Online since 27 September 2022, updated 568 days ago

About this trial

This trial is enrolling individuals with chronic cervical (neck area) spinal cord injuries to test the effect of a technique that combines non-invasive electrical stimulation of the spinal cord with magnetic stimulation of the cortex (brain area). Researchers want to see if this increases nerve signaling in the spinal cord and thus improves arm and hand function. In in animal models, this paired stimulation technique strengthened spinal connections. If included, participants will receive brain stimulation by a magnet placed near the skull and spinal cord stimulation by electrodes places on the skin near the spinal cord. Final testing will be performed an hour after the stimulation is completed.

Included participants

Gender
All
Age
18 - 80 years
Injury level
C1 - C8
  • Severity (AIS)?
  • Time since injury
    ≥ 1 year
    Healthy volunteers
    Yes
    C1-C8
    Additionally, participants must
    NOT have a history of seizures, stroke, brain tumor, brain abscess, or multiple sclerosis
    NOT have a history of moderate or severe head trauma
    NOT have a shistory of implanted brain/spine/nerve stimulators, pacemaker, cochlear implant etc

    What’s involved

    Type

    Technology

    Details

    If included, participants will receive brain stimulation by a magnet placed near the skull and spinal cord stimulation by electrodes places on the skin near the spinal cord

    Potential benefits

    Main benefits

    Arm/hand function

    Additional benefits

    General health

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 10 Sep 2021
    • Organisation
    • Columbia University
    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 10 Sep 2021
    • Organisation
    • Columbia University

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more