Epidural Electrical Stimulation to Restore Hemodynamic Stability and Trunk Control in People With Spinal Cord Injury

Technology
General health
Online since 18 October 2022, updated 489 days ago

About this trial

This trial is enrolling individuals with cervical and upper thoracic spinal cord injuries to test the effect of spinal cord stimulation on low blood pressure and trunk stability. This study uses implanted electrodes placed next to the spinal cord to modify spinal cord function. Investigators want to see how the stimulation affects orthostatic hypotension, which is low blood pressure that may occur when a person sits up from lying down, causing dizziness or lightheadedness. If included, participants will undergo implantation of stimulation electrodes and a neurostimulator, followed by multiple study visits. Final testing will be performed after around 26 months, including measures of blood pressure, trunk stability, spasticity, and overall functional independence.

Included participants

Gender
All
Age
18 - 70 years
Injury level
C3 - T6
Time since injury
≥ 1 month
  • Injury type
  • Traumatic

    Non-traumatic

    Healthy volunteers
    No
    C3-T6
    Additionally, participants must
    have confirmed hypotension

    What’s involved

    Type

    Technology

    Details

    There are no details yet

    Potential benefits

    Main benefits

    General health

    Additional benefits

    Arm/hand function

    Spasticity

    Standing/walking/mobility

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 29 Nov 2021
    • Organisation
    • Ecole Polytechnique Fédérale de Lausanne
    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 29 Nov 2021
    • Organisation
    • Ecole Polytechnique Fédérale de Lausanne

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more