Brain Activity Patterns in Persons With Spinal Cord Injury and Neuropathic Pain After a Virtual Walking Training Program

Rehabilitation

Pain

Online since 8 April 2024, updated 100 days ago

About this trial

This pilot study is enrolling 12 individuals with chronic spinal cord injury to test the effect of virtual walking therapy on neuropathic pain. If included, participants will receive virtual walking therapy over a period of six weeks. The participant's will see themselves walk from a third-person view as their head and trunk are projected over the feet of an actor walking. Changes in brain activity (functional Magnetic Resonance Imaging (fMRI)) and brain metabolism (Magnetic Resonance Spectroscopy (MRS) will be measured. Final testing for pain and brain chemistry will be performed after 6 weeks of virtual walking therapy and after four weeks followup.

Included participants

Gender

All

Age

≥ 18 years

Injury level

C1 - S5

Severity (AIS)?

Time since injury

≥ 1 year

Injury type

Traumatic

Healthy volunteers

C1-S5

Additionally, participants must

Be able to draw with a pen.

Be able to swing their arms.

Not have epilepsy.

What’s involved

Type

Rehabilitation

Details

-participants will receive Virtual Walking therapy as part of the clinical routine, physiotherapeutical assessment, MRS and fMRI - Final testing will be performed 4 weeks after 6 weeks of virtual walking therapy (at 10 weeks).

Potential benefits

Main benefits

Pain

Additional benefits

Arm/hand function

Mental health and psychosocial factors

Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

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