COMMAND Early Feasibility Study: Implantable BCI to Control a Digital Device for People With Paralysis

About this trial

This trial is enrolling 5 individuals with severe motor impairment (including spinal cord injuries) to test the safety and feasibility of an implantable brain-computer-interface (BCI) device, the Synchron motor neuroprosthesis. BCI is a technique using a computer and connected electrodes on the brain to record brain activity that could be used to control an external digital device. The Synchron device is inserted in the cerebral cortex by way of the jugular vein (endovascular). Once in place, the device detects and wirelessly transmits brain signals, such as those for motor intent. If included, participants will undergo a minimally invasive surgical procedure to implant the BCI device. Final safety testing will be done after 12 months.