Deep Brain Stimulation of the Lateral Hypothalamus to Augment Motor Function of Patients With Spinal Cord Injury

Technology
Standing/walking/mobility
Online since 13 July 2022, updated 6 days ago

About this trial

This is small trial enrolling 3 participants with chronic incomplete spinal cord injuries to test the effect of stimulating deeper parts of the brain through surgically implanted electrodes (deep brain stimulation - DBS). Researchers want to see if DBS improves leg motor function; they speculate that DBS combined with direct (epidural) stimulation of the lumbar spinal cord might improve recovery. If included, participants will undergo surgery for implantation of the electrodes into deeper parts of the brain. DBS training sessions will be performed 3 times per week for 3 months. The total duration of the study will be 7-8 months.

Included participants

Gender
All
Age
18 - 65 years
Injury level
C1 - S5
  • Severity (AIS)?
  • AIS-C
    AIS-D
    Time since injury
    12 months - 65 years
  • Injury type
  • Traumatic

    Healthy volunteers
    No
    C1-S5
    Additionally, participants must
    NOT have epilepsy.
    NOT have an active implanted cardiac device.

    What’s involved

    Type

    Technology

    Details

    - Participants will undergo surgery for implantation of the electrodes into deeper parts of the brain (lateral hypothalamus). - DBS training sessions will be performed 3 times per week for 3 months. - The total duration of the study will be 7-8 months.

    Potential benefits

    Main benefits

    Standing/walking/mobility

    Additional benefits

    General health

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Recruitment
    • Unknown
    • Trial start date
    • 14 Jun 2021
    • Organisation
    • Centre Hospitalier Universitaire Vaudois
    • Recruitment
    • Unknown
    • Trial start date
    • 14 Jun 2021
    • Organisation
    • Centre Hospitalier Universitaire Vaudois

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more