Random Noise Stimulation to Enhance Cortical Drive & Improve Hand Function

About this trial

This trial is recruiting individuals with chronic, incomplete cervical spinal cord injuries to test the effect on arm function of a type of brain stimulation (transcranial Random Noise Stimulation – tRNS) in combination with arm/hand training. tRNS is a non-invasive technique that applies low alternating electrical current with changing intensity and frequency to the brain using electrodes on the scalp. Random noise is a special type of brain stimulation that most people cannot feel but is believed to improve limb function. Participants will receive 3 days of tRNS and 3 days of sham (inactive) tRNS stimulation or 3 days of transcranial direct current stimulation (tDCS) and 3 days of sham-tDCS stimulation. Each stimulation type will be delivered during the first 20 minutes of the functional task practice. The communication between brain and spinal cord will be evaluated. Muscle response, change in strength and change in sensory function will be recorded. Final testing will be performed after 2 weeks.