Epidural and Dorsal Root Stimulation in Humans With Spinal Cord Injury
About this trial
This trial is enrolling individuals with chronic spinal cord injuries to test the effect of combining two spinal cord stimulation methods on movement and other bodily functions. One technique, epidural stimulation, activates spinal cord nerve networks using implanted electrodes placed next to the spinal cord. The other method, dorsal root stimulation, uses a similar approach to activate spinal nerve roots close to the spinal cord. Electrodes are implanted using a needle inserted through the skin and are removed when the study is completed. The study will explore whether this combined stimulation modifies spinal cord function related to movement. If selected, participants will undergo surgery for the implantation of the electrodes, and then will receive 10 rehabilitative sessions. Researchers will measure nerve function (electrophysiology) and movement, including overground walking. The study includes questionnaires for participants to assess changes in bowel, bladder, sexual function, and spasticity. Final testing will occur after about 4 weeks.
Included participants
Traumatic
What’s involved
Type
Details
Surgery for the implantation of the electrodes next to the spinal cord 10 rehabilitative session Electrophysiological ad biomechanical testing Surgery to remove the electrodes
Potential benefits
Main benefits
General health
Additional benefits
Bladder health
Bowel health
Sensory function
Sexual health
Spasticity
Standing/walking/mobility
Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.
Wings for Life supports SCITrialsFinder
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more- Trial recruitment status
- Recruiting
- Trial start date
- 24 Sep 2021
- Organisation
- Mayo Clinic
- Trial recruitment status
- Recruiting
- Trial start date
- 24 Sep 2021
- Organisation
- Mayo Clinic
About this trial
Included participants
What’s involved
Potential benefits
Wings for Life supports SCITrialsFinder
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more