NEUROwave - Extracorporeal Shock Wave Therapy (ESWT) in Acute Traumatic Complete (AIS A) and Incomplete (AIS B-D) Cross-sectional Lesions on Motor and Sensory Function Within Six Months After Injury

General health
Online since 5 November 2021, updated 959 days ago

About this trial

This trial is recruiting individuals with acute spinal cord injuries to test the effect of non-invasive low energy extracorporeal shockwave therapy (ESWT) on recovery. ESWT uses an acoustic shockwave which carries energy to the bones, tendons and other soft tissue. It is commonly used to treat kidney stones and in physical therapy. Researchers believe the therapy can preserve nerves that are vulnerable to secondary effects of SCI, e.g. inflammation, scarring, edema. Trial participants will receive either 1) ESWT; or 2) sham-ESWT within 48 hours of spinal cord injury. The device will be applied 5 segments above and below the injury level of the spinal cord and to the soles of the feet. Final testing will be performed after 6 months. This is a one-time treatment. Changes in motor or sensory function will be measured for up to 6 months.

Included participants

Gender
All
Age
18 - 99 years
Injury level
C1 - S5
  • Severity (AIS)?
  • AIS-A
    AIS-B
    AIS-C
    AIS-D
    Time since injury
    ≤ 24 hours
  • Injury type
  • Traumatic

    Healthy volunteers
    No
    C1-S5
    Additionally, participants must
    NOT have implanted device, e.g. pacemaker

    What’s involved

    Type

    Observational

    Details

    The participant will receive either 1) ESWT or 2) sham-ESWT within 48 hours of the spinal cord injury. The device will be applied 5 segments above and below the injury level of the spinal cord and to the soles of the feet. Final testing will be performed after 6 months.

    Potential benefits

    Main benefits

    General health

    Additional benefits

    Arm/hand function

    Bladder health/function

    Sensory function

    Spasticity

    Standing/walking/mobility

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 2 Jul 2020
    • Organisation
    • AUVA
    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 2 Jul 2020
    • Organisation
    • AUVA

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more