Effects of Paired Associative Nerve Stimulation on Spinal Cord Injury Subjects
About this trial
This clinical trial is enrolling individuals with chronic incomplete spinal cord injuries to study the combined effects of magnetic brain stimulation and electrical spinal stimulation. Participants will receive transcranial magnetic stimulation (TMS), a non-invasive technique which uses a magnetic field to stimulate the brain. At the same time, electrical stimulation (trans-spinal direct current stimulation - tsDCS) will be applied to the spinal cord using skin-surface electrodes attached to the trunk. Together this repetitive stimulation combination is called paired associative stimulation (PAS), which has been shown to increase muscle function by increasing nerve activity, and thereby muscle strength and voluntary function. Paired stimulation will be combined with cycling exercises. If selected for the trial, participants will be randomly assigned to one of five study groups: four groups will receive stimulation using different settings, while one group (control) will receive sham (inactive) stimuli. Motor function and strength will be measured.
Included participants
Traumatic
Non-traumatic
What’s involved
Type
Details
One visit with transcranial magnetic stimulation (TMS), trans-spinal direct current stimulation (tsDCS) and leg cycling exercise Baseline and follow-up assessments before and after the intervention
Potential benefits
Main benefits
Standing/walking/mobility
Additional benefits
General health
Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.
Wings for Life supports SCITrialsFinder
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more- Trial recruitment status
- Recruiting
- Trial start date
- 9 Dec 2019
- Organisation
- Taipei Medical University Hospital
- Trial recruitment status
- Recruiting
- Trial start date
- 9 Dec 2019
- Organisation
- Taipei Medical University Hospital
About this trial
Included participants
What’s involved
Potential benefits
Wings for Life supports SCITrialsFinder
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more