Restorative Neuromodulation for Upper Extremity Functions

Technology
Arm/hand function
Online since 4 November 2021, updated 838 days ago

About this trial

This is a clinical trial to investigate the effect of trans-spinal electrical stimulation (tsES) on reaching and grasping in individuals with chronic cervical (neck area) spinal cord injury or traumatic brain injury. tsES is a non-invasive electrical stimulation technique that applies surface electrodes to the skin. This electrical current is thought to activate nerve circuits in the spinal cord; this might improve function of arms, hands and fingers. This study will measure the effectiveness of tsES on motor recovery and muscle strength. Researchers hope to better understand how the stimulation works, using high-resolution nerve measurements (electrophysiology) and biomedical imaging. Participants will receive tsES and participate in follow-up assessments of arm and hand function over a period of 12 months.

Included participants

Gender
All
Age
19 - 65 years
Injury level
C1 - C7
  • Severity (AIS)?
  • AIS-A
    AIS-B
    AIS-C
    AIS-D
    Time since injury
    1 year - 65 years
  • Injury type
  • Traumatic

    Vertebrae fracture

    Traumatic brain injury

    Healthy volunteers
    Yes
    C1-C7
    Additionally, participants must
    be unable to grip or reach independently, and requires assistance for daily living activities
    NOT have received botox injection in prior 6 months
    NOT receiving treatments for either pain management or spasticity or depression

    What’s involved

    Type

    Technology

    Details

    Trans-spinal electrical stimulation (tsES) with surface electrodes applied at the neck region Follow-up assessments of arm and hand function over a period of 12 months (the duration and frequency of stimulation is not specified)

    Potential benefits

    Main benefits

    Arm/hand function

    Additional benefits

    General health

    Spasticity

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Ended
    • Trial start date
    • 1 May 2019
    • Organisation
    • The Hong Kong Polytechnic University
    • Trial recruitment status
    • Ended
    • Trial start date
    • 1 May 2019
    • Organisation
    • The Hong Kong Polytechnic University

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more