An Exercise Intervention to Reduce Neuropathic Pain and Brain Inflammation After Spinal Cord Injury

Technology
Pain
Online since 16 April 2024, updated yesterday

About this trial

This trial is enrolling 13 individuals with sub-acute spinal cord injury (3-24 months post injury) to test the effect of aerobic exercise (rowing) facilitated by functional electric stimulation (FES) on neuropathic pain. FES is a technique to use skin-surface electrodes to activate paralyzed muscles. If included, participants will either receive: a) 12 weeks of FES-rowing training followed by 12 weeks of standard of care; or b) 12 weeks of standard of care followed by 12 weeks of FES-rowing training. Final testing for changes in pain, brain structure, and brain inflammation will be performed after 12 weeks.

Included participants

Gender
All
Age
18 - 50 years
Injury level
C5 - S5
  • Severity (AIS)?
  • AIS-A
    AIS-B
    AIS-C
    Time since injury
    3 months - 24 months
    Healthy volunteers
    No
    C5-S5

    What’s involved

    Type

    Technology

    Details

    -participants will receive either 1) 3 sessions per week for 12 weeks FES-rowing exercices or 2) treatment as usual -final testing will be after 12 weeks

    Potential benefits

    Main benefits

    Pain

    Additional benefits

    General health

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Active
    • Trial start date
    • 20 Feb 2020
    • Organisation
    • Spaulding Rehabilitation Hospital
    • Trial recruitment status
    • Active
    • Trial start date
    • 20 Feb 2020
    • Organisation
    • Spaulding Rehabilitation Hospital

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more