Nerve Transfer After Spinal Cord Injury- Multi-center

Surgery

Arm/hand function

Online since 21 February 2024, updated 57 days ago

About this trial

This is a trial to test the effect of nerve transfer surgery on hand function and quality of life after spinal cord injury. This intervention constitutes surgical transfer of an intact nerve to a target nerve attached to a muscle that has significant weakness or paralysis. If included, the participant will undergo nerve transfer surgery and undergo hand therapy and occupational therapy 2 weeks after the surgery, for 1 hour, 1-2 times per week, for 48 months. Final testing will be performed after the therapy is completed including upper extremity and hand function assessments.

Included participants

Gender

All

Age

18 - 65 years

Injury level

C4 - C8

Severity (AIS)?

AIS-A

AIS-B

Time since injury

≤ 36 months

Injury type

Traumatic

Non-traumatic

Healthy volunteers

C4-C8

Additionally, participants must

have a spinal cord injury for less than 36 months.

have a neurological level of injury between C4-C8

have one of the following ASIA impairment scale (AIS):

What’s involved

Type

Surgery

Details

Nerve transfer surgery Two weeks after the surgery, the participant will undergo 1-hour sessions of hand therapy and occupational, 1-2 times per week, for 48 months. Final testing after the therapy is completed including upper extremity and hand function assessments.

Potential benefits

Main benefits

Arm/hand function

Additional benefits

General health

Mental health and psychosocial factors

Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

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