Nerve Transfer After Spinal Cord Injury- Multi-center

Surgery
Arm/hand function
Online since 21 February 2024, updated 49 days ago

About this trial

This is a trial to test the effect of nerve transfer surgery on hand function and quality of life after spinal cord injury. This intervention constitutes surgical transfer of an intact nerve to a target nerve attached to a muscle that has significant weakness or paralysis. If included, the participant will undergo nerve transfer surgery and undergo hand therapy and occupational therapy 2 weeks after the surgery, for 1 hour, 1-2 times per week, for 48 months. Final testing will be performed after the therapy is completed including upper extremity and hand function assessments.

Included participants

Gender
All
Age
18 - 65 years
Injury level
C4 - C8
  • Severity (AIS)?
  • AIS-A
    AIS-B
    Time since injury
    ≤ 36 months
  • Injury type
  • Traumatic

    Non-traumatic

    Healthy volunteers
    No
    C4-C8
    Additionally, participants must
    have a spinal cord injury for less than 36 months.
    have a neurological level of injury between C4-C8
    have one of the following ASIA impairment scale (AIS):

    What’s involved

    Type

    Surgery

    Details

    Nerve transfer surgery Two weeks after the surgery, the participant will undergo 1-hour sessions of hand therapy and occupational, 1-2 times per week, for 48 months. Final testing after the therapy is completed including upper extremity and hand function assessments.

    Potential benefits

    Main benefits

    Arm/hand function

    Additional benefits

    General health

    Mental health

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 13 Apr 2020
    • Organisation
    • Washington University School of Medicine
    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 13 Apr 2020
    • Organisation
    • Washington University School of Medicine

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more