Improving Hand Recovery With Neuromodulation in Tetraplegia

Technology
Arm/hand function
Online since 4 November 2021, updated 838 days ago

About this trial

This trial is enrolling individuals with chronic incomplete cervical (neck area) spinal cord injuries to test the effects of brain stimulation on motor function. The study uses transcranial direct current stimulation (tDCS) to activate brain nerves responsible for arm and hand movements. tDCS uses painless, non-invasive electrical stimulation via surface electrodes attached to the scalp. The stimulation will be done as a combinational therapy with intensive physical therapy (rehabilitation) of the hand and arm. If selected for the study, participants will randomly be assigned to one of two study groups: 1) receiving 20 minutes active tDCS followed by two hours of upper extremity physical therapy, or 2) receiving 20 minutes of sham (non-functioning) tDCS followed by two hours of upper extremity therapy. The study will measure mobility, independence, including self-care, breathing function and sphincter management. Changes in arm and hand function will also be assessed.

Included participants

Gender
All
Age
18 - 65 years
Injury level
C4 - C7
  • Severity (AIS)?
  • AIS-B
    AIS-C
    AIS-D
    Time since injury
    1 year - 65 years
  • Injury type
  • Traumatic

    Healthy volunteers
    No
    C4-C7
    Additionally, participants must
    NOT have implanted device, e.g. pacemaker

    What’s involved

    Type

    Technology

    Details

    One 20 minute session of active transcranial direct current stimulation, followed by 2 hours of intensive motor therapy of the more affected upper extremity.

    Potential benefits

    Main benefits

    Arm/hand function

    Additional benefits

    General health

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Ended
    • Trial start date
    • 1 Jul 2019
    • Organisation
    • University of Kentucky
    • Trial recruitment status
    • Ended
    • Trial start date
    • 1 Jul 2019
    • Organisation
    • University of Kentucky

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more