Improving Hand Recovery With Neuromodulation in Tetraplegia

About this trial

This trial is enrolling individuals with chronic incomplete cervical (neck area) spinal cord injuries to test the effects of brain stimulation on motor function. The study uses transcranial direct current stimulation (tDCS) to activate brain nerves responsible for arm and hand movements. tDCS uses painless, non-invasive electrical stimulation via surface electrodes attached to the scalp. The stimulation will be done as a combinational therapy with intensive physical therapy (rehabilitation) of the hand and arm. If selected for the study, participants will randomly be assigned to one of two study groups: 1) receiving 20 minutes active tDCS followed by two hours of upper extremity physical therapy, or 2) receiving 20 minutes of sham (non-functioning) tDCS followed by two hours of upper extremity therapy. The study will measure mobility, independence, including self-care, breathing function and sphincter management. Changes in arm and hand function will also be assessed.