Spinal Cord Stimulation and Autonomic Response in People With SCI.
About this trial
This is a trial to test the effect of stimulating the spinal cord, either with an implanted electrode placed next to the spinal cord (epidural spinal cord stimulation: eSCS) or via surface stimulation (transcutaneous spinal cord stimulation: tSCS), on blood pressure when the participant sits upright from lying down (orthostatic hypotension) and bladder, bowel, and sexual function. Individuals with a spinal cord injury who have previously been implanted with an epidural stimulator will be invited to participate in 2 visits (one screening visit to determine eligibility and one eSCS + measurement visit). If participants with SCI who do not have an epidural stimulator are included, they will participate in either 4 study visits (1 screening visit and 3 times 1-hour tSCS + measurement visits) or 21 study visits (1 screening visit, 5 times 1-hour tSCS + measurement, and 15 tSCS only visits). All measurements will be done in a lying and an upright position.
Included participants
Traumatic
Non-traumatic
Ischemia
What’s involved
Type
Details
Individuals who have previously been implanted with an epidural stimulator will be invited to participate in 2 visits, comprising one screening visit to determine eligibility and one eSCS + measurement visit. Individuals who do not have an epidural stimulator will participate in either 4 study visits (1 screening visit and 3 times 1-hour tSCS + measurement visits) or 21 study visits (1 screening visit, 5 times 1-hour TSCS + measurement, and 15 tSCS only visits). All measurements will be done in a lying and an upright position.
Potential benefits
Main benefits
General health
Additional benefits
Bladder health
Bowel health
Mental health
Sexual health
Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.
Wings for Life supports SCITrialsFinder
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more- Trial recruitment status
- Unknown
- Trial start date
- 1 Feb 2020
- Organisation
- University of Calgary
- Trial recruitment status
- Unknown
- Trial start date
- 1 Feb 2020
- Organisation
- University of Calgary
About this trial
Included participants
What’s involved
Potential benefits
Wings for Life supports SCITrialsFinder
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more