Activity-Dependent Transspinal Stimulation in SCI

About this trial

This is a trial to compare the effect of two training types: 1) step training on a treadmill while the body is supported in a harness (Body Weight Support: BWS) alone compared to 2) BWS-assisted step training in combination with another technique for stimulating the spinal cord via the skin surface to modulate spinal cord activity (transspinal stimulation). This study is designed to determine if transspinal stimulation at several frequencies combined with BWS-assisted step training will have more effect on physiological and clinical tests of neurological functioning including walking than BWS-assisted step training alone. If included in this trial, the participant will be randomly assigned to 20 step training sessions of 1) BWS assisted step training alone (control condition), 2) BWS assisted step training with low frequency transspinal stimulation, or 3) BWS assisted step training with high frequency transspinal stimulation. Before and after each session standardized clinical tests will be performed.