Adipose Stem Cells for Traumatic Spinal Cord Injury

Biological/cell based
General health
Online since 3 November 2021, updated 888 days ago

About this trial

This study is enrolling individuals with spinal cord injuries to test the safety and effect of an experimental stem cell therapy. The cells used are derived from the adipose (fat) tissue of each participant. A minor surgery will be performed to obtain fat from the stomach or thigh. The stem cells will be separated from the fat and allowed to multiply for 4-6 weeks. These stem cells (called adipose-derived mesenchymal stem cells) will be injected by needle into the spinal fluid at the lumbar (lower back area) spine. Besides safety, researchers will measure any sensory or motor improvements. Follow up will occur over a period of 96 weeks.

Included participants

Gender
All
Age
≥ 18 years
Injury level
C5 - T12
  • Severity (AIS)?
  • AIS-A
    AIS-B
    Time since injury
    2 weeks - 1 year
  • Injury type
  • Traumatic

    Healthy volunteers
    No
    C5-T12

    What’s involved

    Type

    Biological/cell based

    Details

    Minor surgery to harvest the adipose tissue from a small incision in you abdomen or thigh. Injection surgery (lumbar puncture) to place the stem cells into the cerebrospinal fluid. Outcome assessments and follow-up up to 96 weeks.

    Potential benefits

    Main benefits

    General health

    Additional benefits

    Arm/hand function

    Mental health

    Sensory function

    Standing/walking/mobility

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Ended
    • Trial start date
    • 5 Dec 2017
    • Organisation
    • Mayo Clinic
    • Trial recruitment status
    • Ended
    • Trial start date
    • 5 Dec 2017
    • Organisation
    • Mayo Clinic

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more