Transcutaneous Electrical Spinal Stimulation to Restore Upper Extremity Functions in Spinal Cord Injury

Technology
Arm/hand function
Online since 30 September 2021, updated 995 days ago

About this trial

This is a study to determine if skin-surface (transcutaneous) electrical stimulation of the spinal cord improves hand function in individuals with chronic cervical (neck area) spinal cord injury (tetraplegia). Researchers want to see if this type of electrical stimulation can enhance conscious motor control of hands and arms by activating spinal cord nerve circuits. This study will apply non-invasive stimulation at the back of the neck (cervical spine) and assess changes in movement and feeling in the hands. After an initial baseline test, there will be two intervention arms: participants will be randomly assigned to either start physical therapy targeting hand function alone, or will start the same physical therapy along with spinal cord stimulation. After the first study arm each participant will be assigned to the other arm. After completion of both arms, long-term effects of the interventions will be assessed. Participants will be in the study for 6 months.

Included participants

Gender
All
Age
21 - 70 years
Injury level
C1 - C7
  • Severity (AIS)?
  • AIS-A
    AIS-B
    AIS-C
    AIS-D
    Time since injury
    ≥ 1 year
  • Injury type
  • Traumatic

    Non-traumatic

    Healthy volunteers
    No
    C1-C7
    Additionally, participants must
    have a spinal cord injury for at least 1 year.
    have a neurological level of injury between C1 and C7.
    have difficulties with hand functions in activities of daily living (e.g. dressing, grooming, feeding).

    What’s involved

    Type

    Technology

    Details

    Attend 2 to 5 sessions of weekly study treatment sessions and testing activities. Available for study treatment and follow-up participation for a duration of 6 months.

    Potential benefits

    Main benefits

    Arm/hand function

    Additional benefits

    General health

    Mental health and psychosocial factors

    Spasticity

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Active
    • Trial start date
    • 27 Dec 2016
    • Organisation
    • University of Washington
    • Trial recruitment status
    • Active
    • Trial start date
    • 27 Dec 2016
    • Organisation
    • University of Washington

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more