Intermittent Hypoxia to Enhance Motor Function After Spinal Cord Injury
About this trial
This trial is enrolling individuals with spinal cord injuries to test the effect of intermittent hypoxia on breathing, sitting, standing, and walking. Intermittent hypoxia briefly delivers exposures of low oxygen, alternated with exposures of normal oxygen. Recent studies have shown that this treatment can strengthen motor nerve function after SCI; beneficial effects have been demonstrated with walking, breathing and limb strength. If selected, participants will undergo a session of intermittent hypoxia and for comparison, a sham-session of normal oxygen on a different day. The procedures will be done in 15 brief (1-2 minute) exposures of low oxygen alternated with 15 brief exposures to normal oxygen. In the sham session, the air delivery will be normal oxygen air alternating with normal room air. At the time of the sessions, participants will not know whether they are receiving intermittent hypoxia or the sham alternative. Outcomes will be assessed after each of the two sessions, measuring performance of certain movement and breathing tasks
Included participants
Traumatic
Non-traumatic
What’s involved
Type
Details
The participant will attend two visits at least 7 days apart, one session of intermittent hypoxia and one session of sham intermittent hypoxia. The order of the sessions will be randomly determined and the participant will not be aware of which treatment he is receiving. Before and after the breathing task, the participant will perform the outcome assessments.
Potential benefits
Main benefits
General health
Additional benefits
Standing/walking/mobility
Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.
Wings for Life supports SCITrialsFinder
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more- Recruitment
- Unknown
- Trial start date
- 10 Jul 2017
- Organisation
- University of Florida
- Recruitment
- Unknown
- Trial start date
- 10 Jul 2017
- Organisation
- University of Florida
About this trial
Included participants
What’s involved
Potential benefits
Wings for Life supports SCITrialsFinder
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more