Randomized Trial of Early Hemodynamic Management of Patients Following Acute Spinal Cord Injury

Drug

Standing/walking/mobility

Online since 8 November 2021, updated 1139 days ago

About this trial

This trial is recruiting individuals with new spinal cord injuries to determine if they have better recovery if their blood pressure (BP) is managed in the emergency room. Participants will be randomly assigned to either have medical management of BP to maintain it within a target range, or will not have medical management of BP, allowing it to fluctuate naturally. The main goals are to assess whether BP management affects sensation, strength, pain, and participation in activities of daily living (feeding, bathing, grooming, walking, etc.).

Included participants

Gender

All

Age

≥ 18 years

Injury level

C1 - T8

Severity (AIS)?

AIS-A

AIS-B

AIS-C

Time since injury

≤ 3 weeks

Injury type

Traumatic

Non-traumatic

Healthy volunteers

C1-T8

Additionally, participants must

NOT have a penetrating injury, e.g. gunshot or knife wound

What’s involved

Type

Drug

Details

For 7 days, the participant’s BP will be maintained with medications as needed within a target range or their BP will not be managed, allowing it to fluctuate without targeting a specific range. Testing session to determine the participant’s recovery at 6 months after the injury.

Potential benefits

Main benefits

Standing/walking/mobility

Additional benefits

Arm/hand function

General health

Mental health and psychosocial factors

Pain

Sensory function

Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

Wings for Life supports SCITrialsFinder

Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

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