Neuroplasticity After Spinal Cord Injury

Technology
General health
Online since 2 November 2021, updated 889 days ago

About this trial

This trial is enrolling individuals with spinal cord injuries who can walk a few steps with or without assistance to test the effect of skin-surface stimulation on arm, leg and walking function. Researchers will use both a non-invasive magnetic brain stimulator and an electrical stimulation device applied to nerves in the arms or legs. Magnetic pulses applied to the head will be combined with specific movements in order to improve strength and function. Participants will receive 15 to 190 therapy sessions that take 2-3 hours. Each SCI participant will be compared to a group of non-injured persons (control group).

Included participants

Gender
All
Age
18 - 85 years
Injury level
C1 - L5
  • Severity (AIS)?
  • AIS-B
    AIS-C
    Time since injury
    ≥ 1 month
  • Injury type
  • Traumatic

    Non-traumatic

    Healthy volunteers
    Yes
    C1-L5
    Additionally, participants must
    be able to grip with both hands and pick up a small object (e.g. a large paperclip) from a table, on own.
    must be able to bend elbow, leg, and foot, to some extent.
    must be able to take a few steps with or without help.

    What’s involved

    Type

    Technology

    Details

    The trial is made up of 5 parts: Part 1: 2-30 sessions, each approximately 2-3 hours long, to measure arm and finger strength/movement. Part 2: 2-30 sessions, each approximately 2-3 hours long, to measure leg strength/movement. Part 3: Up to 40 sessions, each approximately 2 hours long, to measure how well the participant can use both arms. Part 4: Up to 40 sessions, each approximately 2 hours long, to measure how well the participant can use both legs. Part 5: Final visit after 5 months. Note: A detailed explanation of the full extent of what is required can only be obtained directly from the Investigator.

    Potential benefits

    Main benefits

    General health

    Additional benefits

    Arm/hand function

    Standing/walking/mobility

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Unknown
    • Trial start date
    • 28 Jan 2021
    • Organisation
    • Shirley Ryan AbilityLab
    • Trial recruitment status
    • Unknown
    • Trial start date
    • 28 Jan 2021
    • Organisation
    • Shirley Ryan AbilityLab

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more