Neuroplasticity After Spinal Cord Injury

Technology

General health

Online since 2 November 2021, updated 897 days ago

About this trial

This trial is enrolling individuals with spinal cord injuries who can walk a few steps with or without assistance to test the effect of skin-surface stimulation on arm, leg and walking function. Researchers will use both a non-invasive magnetic brain stimulator and an electrical stimulation device applied to nerves in the arms or legs. Magnetic pulses applied to the head will be combined with specific movements in order to improve strength and function. Participants will receive 15 to 190 therapy sessions that take 2-3 hours. Each SCI participant will be compared to a group of non-injured persons (control group).

Included participants

Gender

All

Age

18 - 85 years

Injury level

C1 - L5

Severity (AIS)?

AIS-B

AIS-C

Time since injury

≥ 1 month

Injury type

Traumatic

Non-traumatic

Healthy volunteers

Yes

C1-L5

Additionally, participants must

be able to grip with both hands and pick up a small object (e.g. a large paperclip) from a table, on own.

must be able to bend elbow, leg, and foot, to some extent.

must be able to take a few steps with or without help.

What’s involved

Type

Technology

Details

The trial is made up of 5 parts: Part 1: 2-30 sessions, each approximately 2-3 hours long, to measure arm and finger strength/movement. Part 2: 2-30 sessions, each approximately 2-3 hours long, to measure leg strength/movement. Part 3: Up to 40 sessions, each approximately 2 hours long, to measure how well the participant can use both arms. Part 4: Up to 40 sessions, each approximately 2 hours long, to measure how well the participant can use both legs. Part 5: Final visit after 5 months. Note: A detailed explanation of the full extent of what is required can only be obtained directly from the Investigator.

Potential benefits

Main benefits

General health

Additional benefits

Arm/hand function

Standing/walking/mobility

Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

Wings for Life supports SCITrialsFinder

Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

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