The Safety of ahSC in Chronic SCI With Rehabilitation

About this trial

This trial is recruiting individuals with spinal cord injuries to study the safety and effect of cell transplantation as a treatment. Schwann cells harvested from the sural nerve (located in the lower leg) of each participant will be transplanted into the center of the participant's spinal cord injury. Researchers want to see if these cells promote functional recovery by repairing myelin (insulation) on spinal cord nerves. Potential recovery will be enhanced by fitness and rehabilitation activities before and after transplantation. If selected, participants will undergo surgery to collect the cells and place them into the spinal cord. Enrollment will target 2 participant groups, thoracic level and cervical level. Safety and functional assessments will be done after transplantation at weeks 1 and 2 and months 2 and 6.