Mean Arterial Blood Pressure Treatment for Acute Spinal Cord Injury

Drug
Arm/hand function
Online since 1 November 2021, updated 890 days ago

About this trial

This study is recruiting individuals with acute spinal cord injuries to evaluate the effect of medical management of blood pressure on motor function, sensory function, and quality of life. Participants will either receive treatment to produce slightly higher blood pressure (hypertension), or will be maintained at normal blood pressure for 7 days after injury. The study hypothesis is that inducing higher blood pressure, which is the current clinical practice, does not offer significant benefits to patients when compared to normal blood pressure maintenance.

Included participants

Gender
All
Age
≥ 16 years
Injury level
C1 - T12
  • Severity (AIS)?
  • AIS-A
    AIS-B
    AIS-C
    Time since injury
    ≤ 24 hours
  • Injury type
  • Traumatic

    Healthy volunteers
    No
    C1-T12

    What’s involved

    Type

    Drug

    Details

    The participant will either get medical management to 1) maintain their blood pressure at >=65mmHg or 2) produce slightly higher blood pressure (>=85mmHg) for 7 days after their injury. Neurological examination (ASIA exam) 12 months after the injury.

    Potential benefits

    Main benefits

    Arm/hand function

    Additional benefits

    General health

    Mental health

    Sensory function

    Standing/walking/mobility

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Ended
    • Trial start date
    • 1 Feb 2013
    • Organisation
    • University of Calgary
    • Trial recruitment status
    • Ended
    • Trial start date
    • 1 Feb 2013
    • Organisation
    • University of Calgary

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more