Stimulation With Wire Leads to Restore Cough

Technology
General health
Online since 1 November 2021, updated 841 days ago

About this trial

This study is recruiting individuals with cervical (neck area) spinal cord injuries to test the use of a small electrical device to stimulate the muscles responsible for coughing. The goal of this trial is to determine if stimulation improves the ability to cough effectively, on demand, which is important to help prevent lung infections. The trial includes a minimally invasive surgical procedure over the surface of the spinal cord on the lower back to stimulate the coughing (expiratory) muscles. Participants will practice coughing with stimulation for 10 to 15 minutes, 2-3 times/day for 40 weeks.

Included participants

Gender
All
Age
18 - 75 years
Injury level
C1 - C8
  • Severity (AIS)?
  • AIS-A
    AIS-B
    AIS-C
    AIS-D
    Time since injury
    6 months - 75 years
  • Injury type
  • Traumatic

    Non-traumatic

    Ischemia

    Healthy volunteers
    No
    C1-C8

    What’s involved

    Type

    Technology

    Details

    Surgery to implant the device. Training to learn how to use the device including coughing exercises. Final visit will be 2 years after the surgery.

    Potential benefits

    Main benefits

    General health

    Additional benefits

    Arm/hand function

    Mental health

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Ended
    • Trial start date
    • 1 Apr 2015
    • Organisation
    • MetroHealth Medical Center
    • Trial recruitment status
    • Ended
    • Trial start date
    • 1 Apr 2015
    • Organisation
    • MetroHealth Medical Center

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more