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    "result": {"pageContext":{"pagePath":"/trials/NCT07511244","trial":{"nct_id":"NCT07511244","brief_title":"SCS Therapy for Patients With Bladder and Bowel Dysfunction After SCI","official_title":"Clinical Trial on the Safety and Efficacy of Spinal Cord Stimulation Therapy for Patients With Bladder and Bowel Dysfunction After Spinal Cord Injury","about_trial":"This clinical trial aims to evaluate the safety and efficacy of spinal cord stimulation (SCS) in treating patients with urinary and bowel dysfunction after spinal cord injury (SCI). SCI is a highly disabling condition that can lead to sensory, motor, and autonomic nervous system dysfunction below the injury level. Neurogenic bladder and bowel dysfunction are common sequelae of SCI, seriously affecting patients' quality of life. Currently, clinical treatments can only partially alleviate urinary and bowel dysfunction, and more effective therapeutic approaches are still needed. Existing clinical studies have shown that SCS is gradually being applied to treat neurogenic bladder and bowel dysfunction in SCI patients. SCS can significantly improve urinary efficiency, bladder capacity, compliance, and detrusor pressure in SCI patients, thereby enhancing their quality of life. The main questions this study aims to answer include: 1. Can this protocol help patients restore partial urinary and bowel function? 2. Besides the restoration of partial urinary and bowel function , can the SCS therapy could also help patients to restore the walking function.\n\nPatients with urinary and bowel dysfunction more than 6 months after spinal cord injury will undergo epidural spinal stimulation electrode implantation surgery two weeks after functional assessment. Then the parameter optimization and rehabilitation will last for 6 months. The follow-up records and assessments will be conducted monthly at 2, 4, and 6 months after surgery.","age_from":18,"age_to":60,"ais_a":true,"ais_b":true,"ais_c":true,"ais_d":true,"ais_e":false,"time_since_injury_from":6,"time_since_injury_from_unit":"months","time_since_injury_to":null,"time_since_injury_to_unit":null,"healthy_volunteers":false,"inclusion_criteria":null,"study_type":"interventional","allocation":"N/A","brief_description":"This clinical trial aims to evaluate the safety and efficacy of spinal cord stimulation (SCS) in treating patients with urinary and bowel dysfunction after spinal cord injury (SCI). SCI is a highly disabling condition that can lead to sensory, motor, and autonomic nervous system dysfunction below the injury level. Neurogenic bladder and bowel dysfunction are common sequelae of SCI, seriously affecting patients' quality of life. Currently, clinical treatments can only partially alleviate urinary and bowel dysfunction, and more effective therapeutic approaches are still needed. Existing clinical studies have shown that SCS is gradually being applied to treat neurogenic bladder and bowel dysfunction in SCI patients. SCS can significantly improve urinary efficiency, bladder capacity, compliance, and detrusor pressure in SCI patients, thereby enhancing their quality of life. The main questions this study aims to answer include: 1. Can this protocol help patients restore partial urinary and bowel function? 2. Besides the restoration of partial urinary and bowel function , can the SCS therapy could also help patients to restore the walking function.\n\nPatients with urinary and bowel dysfunction more than 6 months after spinal cord injury will undergo epidural spinal stimulation electrode implantation surgery two weeks after functional assessment. Then the parameter optimization and rehabilitation will last for 6 months. The follow-up records and assessments will be conducted monthly at 2, 4, and 6 months after surgery.","detailed_description":null,"final_testing_performed":"6 months","version_id":2,"emsci_trial":false,"curation_status":"uncurated","overall_recruitment_status":"recruiting","primary_intervention":{"id":5,"name":"Technology","parent_id":null,"icon_name":"technology"},"primary_benefit":{"id":2,"name":"Bladder health/function","parent_id":null,"icon_name":"bladder"},"sex":"All","injury_level_from":"C1","injury_level_to":"S5","start_date":"2024-12-01","organization":"Beijing Tsinghua Chang Gung Hospital","benefits":[{"id":2,"name":"Bladder health/function","parent_id":null,"icon_name":"bladder"},{"id":4,"name":"Bowel health","parent_id":null,"icon_name":"bowel"},{"id":5,"name":"General health","parent_id":null,"icon_name":"general-health"},{"id":6,"name":"Mental health and psychosocial factors","parent_id":null,"icon_name":"mental-health"},{"id":12,"name":"Standing/walking/mobility","parent_id":null,"icon_name":"walking"}],"injuries":[],"interventions":[{"id":4,"name":"Surgery","parent_id":null,"icon_name":"scalpel"},{"id":5,"name":"Technology","parent_id":null,"icon_name":"technology"}],"outcome_measures":[{"id":1,"name":"10 Meter Walking Test (10 MWT)","short_name":"10 MWT","pivot":{"trial_id":8020,"outcome_measure_id":1}},{"id":90,"name":"Neurogenic Bladder Symptom Score","short_name":null,"pivot":{"trial_id":8020,"outcome_measure_id":90}},{"id":91,"name":"Neurogenic Bowel Dysfunction Score (NBD or NBDS)","short_name":"NBD or NBDS","pivot":{"trial_id":8020,"outcome_measure_id":91}},{"id":127,"name":"Short Form 36 (SF-36)","short_name":"SF-36","pivot":{"trial_id":8020,"outcome_measure_id":127}},{"id":158,"name":"Walking Index for Spinal Cord Injury (WISCI) and WISCI II","short_name":"WISCI","pivot":{"trial_id":8020,"outcome_measure_id":158}}],"recovery_mechanisms":[],"published_at":"2026-05-05T14:12:14.000000Z","modified_at":"2026-05-05T14:12:14.000000Z"},"layout":"trial"}},
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